Clinical Trial - Open Access

NIAGARA Clinical Trial Sentiment

Written by Brian Shields | Sep 15, 2024 8:48:47 PM

Key Opinion Leaders React to NIAGARA at #ESMO24

 

Total Impressions 59,776

KOL Sentiment

 -100100Positive

Top Tweets

 

Sentiment Analysis

Doctor Name Sentiment Comment
Neeraj Agarwal, MD, FASCO
POSITIVE
Fantastic discussion of the Niagara trial results by master @PGrivasMDPhD in the @myESMO #ESMO24 presidential session👉Comparison with other adjuvant trials👇perioperative durvalumab with cisplatin chemo is new standard of care due to OS benefit @urotoday @OncoAlert https://t.co/0Vu6oHkZst https://t.co/jvZNdaoF4w
Petros Grivas
POSITIVE
Fantastic atmosphere in Barcelona Presidential symposium with practice changing data including NIAGARA trial #bladdercancer @myESMO #ESMO24 #ESMOAmbassadors @OncoAlert @Uromigos @tompowles1 @DrChoueiri @MyriamChalabi @lab_kok @curijoey @KKronig @AndresC27622123 @peters_solange https://t.co/0KfdqnuyiJ https://t.co/8Hsc3ufYqS
Neeraj Agarwal, MD, FASCO
POSITIVE
Breaking news (practice changing) from @myESMO #ESMO24 👉@tompowles1 presents the 1st results of the ph3 Niagara trial of cisplatin + gemcitabine +|- durvalumab in MIBC #bladdercancer 👉Significant improvement in DFS (HR 0.68) & OS (HR 0.75) with durvalumab @OncoAlert @urotoday https://t.co/CsipAvOLe8
Toni Choueiri, MD
POSITIVE
NIAGARA. Chemo +Durva is a NEW SOC in HIGH RISK PERIOP Muscle-Invasive Bladder Cancer #ESMO24. @tompowles1 does it again! Concomitant @NEJM paper! https://t.co/6H7JzrZnsm
Javier Puente
POSITIVE
#ESMO24 @tompowles1 has presented another practice changing bladder trial!! periop GC+Durva, meets EFS+OS NIAGARA trial Congrats!!!!! https://t.co/EXn2fXAEDf
Tian Zhang, MD, MHS
POSITIVE
Masterful discussion from @PGrivasMDPhD -- placing #NIAGARA in context of our #bladdercancer practice -- neoadjuvant and adjuvant OS benefits. Patients are living longer from earlier use of IO agents. Proposes future trial designs. @myESMO #ESMO24 #ESMOAmbassadors @OncoAlert https://t.co/UDtmsD84Ni
Shilpa Gupta
POSITIVE
#ESMO24 The indomitable & humble @tompowles1 does it again w/ the large practice changing NIAGARA! neoadjuavnt GC durvalumab & adjuvant durva improves EFS & OS compared to GC in MIBC! @montypal @neerajaiims @PGrivasMDPhD @DrRosenbergMSK @apolo_andrea @UroDocAsh @DrChoueiri https://t.co/m4K1q0U9L0
Sabine D. Brookman-May
NEUTRAL
The right questions addressed by @PGrivasMDPhD after NIAGARA trial presentation: ❓should we proceed with adjuvant treatment in ypT0? ❓Is there a role of ctDNA for adjuvant treatment decisions ❓can pts be cured with systemic therapy #BladderSparing approach? @oncodaily #MIBC https://t.co/h9wAhkPSbt
Sergio Vázquez
NEUTRAL
NIAGARA: Probably a new SoC, but we don’t know if it’s better than adjuvant immunotherapy in operable bladder cancer. The pCR is not statistically significant. Fantastic discussion by @PGrivasMDPhD #ESMO24 #bladdecancer https://t.co/SatsnffhvP
Dr Amol Akhade
NEUTRAL
Good discussion @PGrivasMDPhD 👌 👍 many unanswered questions. Important one is Post progression therapy for control arm ? Not there in published paper also ? This is important Data as was asked during discussion. We will need that to see that @VPrasadMDMPH @Timothee_MD @myESMO… https://t.co/DxWMYriziv https://t.co/YmemcNSaMr
Jason Brown
NEUTRAL
The awaited Niagara results are here @tompowles1. Perioperative Durvalumab shows clear PFS and OS benefit in MIBC. 💉pCR rate 33% ‼️PFS HR 0.68 👍🏻OS HR 0.75 ❓ Is adjuvant IO needed for all patients? https://t.co/ZIf5IH68EU
Vinay Prasad MD MPH
NEGATIVE
@SuyogCancer @PGrivasMDPhD @Timothee_MD @myESMO The authors have not even looked at post recurrence data. I think this is a new low @NEJM should have made them report this as condition to publish. Sad day for doctors who want to read science and be able to analyze it properly
Vinay Prasad MD MPH
NEGATIVE
@SuyogCancer @tompowles1 The authors have not even explored post-recurrence data. Pretty bad
Timothée Olivier, MD
NEGATIVE
Where are post-recurrence data? Not available. NIAGARA enrolled in LMIC countries with limited access to best post-recurrence care, which likely led to positive OS. Despite high expectations, NIAGARA did not have a standing ovation, and this is a good sign for oncology! https://t.co/IRvgi78f9H https://t.co/ISWhYi4MWw https://t.co/8fXUNKohQ2