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Mark Lewis, MD, FASCO profile photo
KOL Pulse Profile · 2026

Mark Lewis, MD, FASCO

Hematology Oncology · Intermountain Health · Institution profile ↗

Director, GI Oncology, @Intermountain. Interests: neuroendocrine tumors, cancer syndromes, empathy (even had a Whipple myself). Tweets my own.

Mark Lewis, MD, FASCO (@marklewismd) ranks #8 among US gi cancer KOLs on X in 2026, by engagement from fellow physicians. 29 physicians shared, quoted or replied to their posts this year. Most-discussed trials in 2026: HERIZON-GEA-01, RASolute 302, CIRCULATE. CMS Open Payments lists $49,420 in 2025 general payments.

Mark Lewis, #8 gi cancer KOL in the USA, KOL Pulse 2026 rankings
Mark Lewis, #8 gi cancer KOL in the USA, KOL Pulse 2026 rankings

At a Glance

This Month

What Mark Lewis, MD, FASCO has posted in the last 30 days. Updated November 10, 2026.

No trial posts in the last 30 days.

Who Amplifies Mark Lewis, MD, FASCO

Physicians who reposted Mark Lewis, MD, FASCO’s trial posts most often in 2026.

2026 Rankings

ListUS rankGlobal rankPhysicians engagedPhysician engagements
GI Cancer#8—2933Full ranking

What Colleagues Are Saying About Mark Lewis, MD, FASCO

2026 posts by fellow physicians that mention @marklewismd, quoted word for word.

Highlight of #ASCO26 was being able to share a stage with these giants of GI Oncology that I’ve looked up to and respected for years. Thanks to @YJanjigianMD @marklewismd and @Sarbaji85064063 for joining and making this a great event. @Onco_Nexus @TheGutOncLab https://t.co/2f5I8xtdqo
Nicholas Hornstein (@GIMedOnc) · · View on X ↗

Trials Mark Lewis, MD, FASCO Discussed in 2026

TrialPostsRank among physicians postingLatest
HERIZON-GEA-012#18 of 34Jan 8, 2026
RASolute 3021#11 of 73May 31, 2026
CIRCULATE1#3 of 5May 31, 2026
KEYNOTE-9371#7 of 12Jan 9, 2026
ILUSTRO1#9 of 11Jan 8, 2026

Mark Lewis, MD, FASCO on HERIZON-GEA-01

Dr Daniel Lin @JeffersonUniv summarizes contemporary biomarker-driven management of metastatic gastroesophageal cancer, highlighting added insights from ILUSTRO and HERIZON-GEA-01 #GI26 https://t.co/FqmdFmg0w9
1,259 impressions · View on X ↗
HERIZON-GEA-01 shows PFS benefit for zanidatamab (bispecific anti-her2) + tislelizumab (anti-PD1) + chemo (vs. trastuzumab + chemo) for mGE her2+ cancer #GI26 https://t.co/LhlzkxtGqV
1,254 impressions · View on X ↗

HERIZON-GEA-01 trial profile →

Mark Lewis, MD, FASCO on RASolute 302

Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived #ASCO26 https://t.co/yS9E5kGHs1
1,141,669 impressions · View on X ↗

RASolute 302 trial profile →

Mark Lewis, MD, FASCO on CIRCULATE

ctDNA can clarify the personal benefit of adjuvant chemotherapy, here in stage II colon cancer (from CIRCULATE, LBA3500) Post-op + doesn't mean recurrence is inevitable, and we can be selective in which patients stand to benefit (doubling 3y DFS rates with cape alone!) #ASCO26 https://t.co/HQHsxSebgD
3,065 impressions · View on X ↗

Mark Lewis, MD, FASCO on KEYNOTE-937

Negative trials matter too! Especially given the paradigm shift towards IO in HCC since 2020, it is important (if disappointing) to learn that adjuvant pembrolizumab does not affect survival outcomes per KEYNOTE-937 #GI26 https://t.co/HHrxMNZlnw
3,765 impressions · View on X ↗

KEYNOTE-937 trial profile →

Mark Lewis, MD, FASCO on ILUSTRO

Phase II ILUSTRO data suggest that claudin 18.2 targeting (zolbetuximab) and immunotherapy (nivolumab) don't have to be either/or in metastatic GEJ adenocarcinoma #GI26 https://t.co/q9jbwch2Gy
1,089 impressions · View on X ↗

ILUSTRO trial profile →

Mark Lewis, MD, FASCO’s Most-Engaged Posts in 2026

Their own 2026 posts that fellow physicians reposted most, quoted word for word.

Updated analysis of CheckMate 9DW shows mOS ~ 2 years, ~30% of patients alive at 4 years with ipi/nivo (a remarkable milestone in unresectable HCC!) #GI26 https://t.co/zqgNn4Mt1i
3,432 impressions · View on X ↗
Biliary tract cancer is arguably the GI primary site par excellence for NGS surfacing actionable mutations Lirafugratinib adds another arrow to our FGFR2-targeting quiver (but different toxicity profile -- ⬆️stomatitis, HFS -- for selective inhibition vs. pan-FGFRi) #GI26
3,499 impressions · View on X ↗
I was a freshman in high school when I decided I wanted to be an oncologist I had a meaningful full-circle moment today at #ASCO26 when I met a remarkably articulate young man who, at roughly the same age, has set his sights on joining our field The future is so very bright🌟 https://t.co/yfgOt6yxwd
13,104 impressions · View on X ↗
We need a lot more of these ribbons #ASCO26 https://t.co/2TQqrBFcoc
2,718 impressions · View on X ↗

Industry Payments

CMS Open Payments · 2025 general payments
$49,420 across 52 payments
View the CMS record ↗
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FAQ

How does Mark Lewis, MD, FASCO rank among oncology KOLs in 2026?

Mark Lewis, MD, FASCO ranks #8 among US gi cancer KOLs on X in 2026, based on engagement from fellow physicians (KOL Pulse rankings, updated November 10, 2026).

Which clinical trials does Mark Lewis, MD, FASCO discuss most?

In 2026, Mark Lewis, MD, FASCO posted most often about HERIZON-GEA-01, RASolute 302, CIRCULATE. Each post is quoted word for word on this page with a link to the original.

On which clinical trials is Mark Lewis, MD, FASCO a leading physician voice on X?

Among physicians posting about each trial on X in 2026, Mark Lewis, MD, FASCO ranks #3 of 5 physicians on CIRCULATE, based on engagement from fellow physicians.

Does Mark Lewis, MD, FASCO receive industry payments?

CMS Open Payments lists $49,420 in 2025 general payments. Source: CMS Open Payments, program year 2025.

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KOL Pulse analysis · Reviewed by Brian Shields, Founder, KOL Pulse · Updated