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KOL Pulse · KOL Digest

AI in Oncology

Oncologists in their own words on AI in clinical practice — knowledge tools, patient-facing AI, AI-derived biomarkers, and regulation. Every post verbatim and in full.

Latest edition · September 7, 2026
A randomized trial finds AI trial notifications alone don't move enrollment, Astra drafts five R01s in an hour — and OpenEvidence ships its own models

In this edition: Roupen Odabashian, MD on the randomized trial where AI-triggered trial notifications did not change enrollment — and on launching an AI agent that tracks approvals · Benjamin Herzberg, MD on the slowest step in AI drug development · Jason Locasale on Astra drafting five NIH R01 proposals in about an hour · Jame Abraham, MD on OpenEvidence's new model family · Katy Beckermann, MD on chart-finding time · the Oncology Brothers on bias, privacy, and liability · Arturo Loaiza-Bonilla, MD on verifying AI alignment · Hidehito Horinouchi, MD on the IASLC AI Taskforce surveys · NEJM AI on agentic research workflows.

9 voices · read the edition →
Edition · August 31, 2026
AI spots pancreatic cancer three years early, most oncologists use AI without governance — and Epic points AI at its own code

In this edition: Eric Topol, MD on AI detecting pancreatic cancer up to 3 years before diagnosis · Yan Leyfman, MD on the governance gap — 83% of surveyed oncology clinicians use AI independently, 71% report no institutional policy · Katy Beckermann, MD on Epic running Anthropic's Mythos across its own codebase · Chadi Nabhan, MD on AI tumor twins with Bishoy Faltas, MD.

4 voices · read the edition →
Edition · August 25, 2026
AI-read TILs, 'Peer-Unreviewed' in Annals, 66% physician adoption - and residents beating radiology AI

In this edition: Mali Barbi, MD asks whether AI-read TILs are the next PD-L1 · Ilana Schlam, MD shares AI TIL data from NSABP B-41 · Samer Al Hadidi, MD publishes 'Peer-Unreviewed' in Annals of Internal Medicine and Eric Topol, MD flags it · Karun Neupane, MD on omission errors in AI summaries · Sawyer Bawek, DO on Doximity's 66% physician AI adoption · Laura Heacock, MD on residents outperforming radiology AI · Allan Pereira, MD, PhD on the LiON prospective AI reader in Nature Medicine · Hidehito Horinouchi, MD and Fabio Moraes, MD preview AI at WCLC26 · Zeke Emanuel, MD on AI's improvement curve · Anish Koka, MD debates the Khosla thesis · Andrew Portuguese, MD builds with local AI · Arturo Loaiza-Bonilla, MD on Amara's law and the AI Oncology Revolution podcast · Shiv Rao, MD on Abridge's thesis · Yair Einhorn on AI's limits in biotech R&D · Bo Wang on the AI-designed individualized vaccine trial · VJHemOnc on an ML six-gene myeloma signature

18 voices · read the edition →
Edition · August 18, 2026
JAMA: the case for AI alone, vibe coding, and a hallucinated peer-reviewed pub

In this edition: JAMA's new Perspective argues AI alone may exceed physicians on cognitive medical tasks · co-authors Zeke Emanuel, MD and Vinod Khosla make the case · Eric Topol, MD flags the argument · Yakup Ergün, MD largely agrees — and says what physicians still own · physician-founder Joseph Younis, MD on the paper's conflicts of interest · Santhosh Ambika, MD on workforce oversupply · Jeff Ryckman, MD on Abridge saving an hour a day — and on an EviCore denial built on AI-hallucinated literature · Jean-Charles Soria, MD on AI in pharma R&D · The ASCO Post's AI week in review.

12 voices · read the edition →
Edition · August 12, 2026
AI is replacing the reference tools, and the journals are setting limits

In this edition: Aaron Goodman, MD on AI replacing UpToDate · David S. Hong, MD on building his own RAS dashboard · Noah Lindenberg, MD on the limits of OpenEvidence · Yüksel Ürün, MD on where JAMA draws the line between AI assistance and authorship · Hashem El-Serag, MD on JAMA's new manuscript guidance · The ASCO Post on a study in which physicians kept following incorrect AI classifications.

6 voices · read the edition →
Edition · August 10, 2026
AI is already in the clinic

In this edition: Aaron Goodman, MD on AI replacing UpToDate in daily use · Katy Beckermann, MD, PhD on AI tools in the community clinic · Estela Rodriguez, MD on patients bringing AI answers to the visit · Antonio Giordano, MD, PhD on AI-scored TROP2 · Andrew Pannu on AI in biopharma intelligence teams · Jame Abraham, MD on Cleveland Clinic's AI Summit, Aug 28.

6 voices · read the edition →
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