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KOL Pulse Insights Blog

Oncology KOL Intelligence, decoded.

Key opinion leader trends, clinical-trial commentary, conference recaps, and AI-native intelligence on the physicians shaping oncology practice — straight from the social conversation.

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Who Drove the ESMO 2026 Conversation, and Who Amplified It
Nov 11, 2026, 4:24:42 AM Brian Shields

Who Drove the ESMO 2026 Conversation, and Who Amplified It

1,199 physicians discussed ESMO 2026 on X. Top KOLs, amplifiers, trials and US states for lung, breast, GU and GI cancer, with 8 public network maps.

kol reactionsesmo 2026
“New Standard of Care”? Lung Cancer KOLs on KRASCENDO-1 and ESMO26
Oct 31, 2026, 2:50:02 AM Brian Shields

“New Standard of Care”? Lung Cancer KOLs on KRASCENDO-1 and ESMO26

ESMO26 lung KOL reactions: KRASCENDO-1 OS HR 0.56, PERSEE PFS HR 0.56, DeLLphi-305 OS HR 0.42, and four China-only ADC trials in NSCLC.

lung cancerkol reactionsesmo 2026
ESMO 2026: Oncology is the Tip of the Spear for AI in Healthcare
Oct 30, 2026, 8:48:11 AM Brian Shields

ESMO 2026: Oncology is the Tip of the Spear for AI in Healthcare

ESMO 2026: oncology leads OpenEvidence use (JAMA), and digital opinion leaders moved INTerpath-001, NADINA and KRASCENDO-1 debates at X speed.

kol reactionsesmo 2026
ESMO 2026 Day 3: Top Trials and KOL Reactions
Oct 26, 2026, 6:06:19 AM Brian Shields

ESMO 2026 Day 3: Top Trials and KOL Reactions

ESMO 2026 Day 3: KRASCENDO-1 and the crossover question, SAFFRON, HARMONi-GI1, CLARITY-Gastric01, PERSEE, LITESPARK-012, NADINA and more, with physician reactio…

lung cancerbreast cancerkol reactions
ESMO 2026: Top Melanoma Trials and KOL Voices
Oct 25, 2026, 7:43:15 AM Brian Shields

ESMO 2026: Top Melanoma Trials and KOL Voices

ESMO 2026 Madrid melanoma, October 23–26: investigational INTerpath-001 led physician discussion, followed by the NADINA 3-year update, STARBOARD and TIL data, …

kol reactionsesmo 2026melanoma
ESMO 2026: Top GI Cancer Trials and KOL Voices
Oct 25, 2026, 7:43:03 AM Brian Shields

ESMO 2026: Top GI Cancer Trials and KOL Voices

ESMO 2026 Madrid GI cancers, October 23–26: HARMONi-GI1, CLARITY-Gastric01, HERIZON-GEA-01, SANO, G-HOPE-001, IROCAS and AZUR-1, with verbatim physician reactio…

kol reactionsesmo 2026gastrointestinal cancer
ESMO 2026: Top Gynecologic Cancer Trials and KOL Voices
Oct 25, 2026, 7:42:53 AM Brian Shields

ESMO 2026: Top Gynecologic Cancer Trials and KOL Voices

ESMO 2026 Madrid gynecologic cancers, October 23–26: TroFuse-005 and KEYNOTE-C93 from Presidential Symposium III, plus NRG-GY020, DUO-E and BEHOLD-1, with verba…

kol reactionsesmo 2026ovarian cancer
ESMO 2026: Top Breast Cancer Trials and KOL Voices
Oct 25, 2026, 7:42:44 AM Brian Shields

ESMO 2026: Top Breast Cancer Trials and KOL Voices

ESMO 2026 Madrid breast cancer, October 23–26: NATALEE, KEYNOTE-B49, PANKU-Breast01, FOURLIGHT-1, SWITCH, BRIDGET, OptiTROP-Breast01 and DESTINY-Breast09, with …

breast cancerkol reactionsesmo 2026
ESMO 2026: Top Lung Cancer Trials and KOL Voices
Oct 25, 2026, 7:42:33 AM Brian Shields

ESMO 2026: Top Lung Cancer Trials and KOL Voices

ESMO 2026 Madrid lung cancer, October 23–26: DeLLphi-305, KRASCENDO-1, SAFFRON, PERSEE, OptiTROP-Lung06, PANKU-Lung01 and HERON-Lung01, with verbatim physician …

lung cancerkol reactionsesmo 2026
ESMO 2026: Top GU Cancer Trials and KOL Voices
Oct 25, 2026, 7:42:21 AM Brian Shields

ESMO 2026: Top GU Cancer Trials and KOL Voices

ESMO 2026 Madrid GU cancers, October 23–26: VOLGA, KEYNOTE-866, DASL-HiCaP, LITESPARK-012 and TALAPRO-3, FDA approved October 26, with verbatim physician reacti…

kol reactionsesmo 2026bladder cancer
ESMO 2026 Days 1–2: Top Trials and KOL Reactions
Oct 25, 2026, 4:04:36 AM Brian Shields

ESMO 2026 Days 1–2: Top Trials and KOL Reactions

ESMO 2026 Days 1-2: a standing ovation for DeLLphi-305 and the crossover question physicians raised, plus INTerpath-001, VOLGA, NATALEE, PANKU-Breast01 and more…

lung cancerbreast cancerkol reactions
The ESMO 2026 Debates from the KOL Social Media Threads
Oct 24, 2026, 12:19:39 PM Brian Shields

The ESMO 2026 Debates from the KOL Social Media Threads

ESMO 2026 physician debates on X, verbatim: INTerpath-001 vs neoadjuvant IO, NATALEE's nominal OS p-value, me-too HER2 ADCs, pCR vs EFS in bladder cancer, KEYNO…

breast cancerkol reactionsesmo 2026
AI-Native Workflows with Your Favorite Tools: 5 Prompts to Copy
Oct 24, 2026, 3:11:19 AM Brian Shields

AI-Native Workflows with Your Favorite Tools: 5 Prompts to Copy

Paste a KOL Pulse trial or conference page into NotebookLM, Perplexity, Claude or ChatGPT. Five copy-ready prompts: trial timelines, trial-vs-trial tables, sent…

AI-NativeAI Workflowsesmo 2026
ENERGIZE and KEYNOTE-866: Two Negative Phase 3 MIBC Trials at ESMO 2026, and the NIAGARA Question
Oct 24, 2026, 2:32:23 AM Brian Shields

ENERGIZE and KEYNOTE-866: Two Negative Phase 3 MIBC Trials at ESMO 2026, and the NIAGARA Question

ESMO 2026: perioperative nivolumab (ENERGIZE, EFS HR 0.94) and pembrolizumab (KEYNOTE-866, EFS HR 0.88, OS HR 1.00) with gem/cis did not improve EFS in cisplati…

mibckol reactionsesmo 2026
The INTerpath-001 Leak: An Embargo Break, a 25% Drop, and What Oncologists Said
Oct 22, 2026, 11:49:54 AM Brian Shields

The INTerpath-001 Leak: An Embargo Break, a 25% Drop, and What Oncologists Said

ESMO lifted the LBA1 embargo after INTerpath-001 results leaked early: RFS HR 0.58 (95% CI 0.45–0.75). Moderna fell 25%. What oncologists and investors said.

kol reactionsinterpath-001esmo 2026

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